As a prescription antidepressant, Remeron SolTab (mirtazapine) is indicated for the treatment of major depressive disorders. However, recent evidence lends weight to the long-suspected link between Remeron Soltab and catastrophic complications. Patients receiving Remeron treatment may significantly increase their risk of developing significant blood and bone marrow abnormalities, liver problems, and suicidal ideations. Subsequently, the use of this antidepressant by pregnant women may result in severe, life-threatening congenital birth defects.
If you or a loved one has been injured by Remeron SolTab, you should contact our lawyers immediately for a free confidential case evaluation. You may be entitled to compensation for your injuries and we can help.
Remeron SolTab Lawsuit Overview
Having already established itself as a successful medication in the pharmaceutical industry, Remeron SolTab has been a key contributer to the treatment of major depressive disorders since January 12, 2001. As a product of Organon USA Inc., Remeron SolTab has boasted the approval of the U.S. Food and Drug Administration (FDA) for approximately 11 years. Subsequently, its distinct mechanism of action has demonstrated a propensity to treat the following conditions:
- Panic disorders
- Generalized anxiety
- Sleep disorders
- Chronic fatigue
- Irritable bowel syndrome (IBD)
Mirtazapine, the active ingredient found in Remeron SolTab, resides in a family of drugs known as tetracyclic antidepressants. As a tetracyclic antidepressant, mirtazapine has the inherent ability to inhibit the reuptake of neurotransmitters such as serotonin and norepinephrine. While the chemical reactions of these neurotransmitters remain ambiguous, their presence in the central nervous system is believed to elevate mood. Therefore, by preventing their absorption, excessive amounts of these chemicals are able to stimulate nerve receptors and influence an individual’s mood.
Unfortunately, the pharmacodynamics of Remeron SolTab may also be responsible for a variety of associated complications with varying degrees of severity. Subsequently, patients receiving Remeron Soltab treatment may significantly increase their risk of developing significant blood and bone marrow abnormalities, liver problems, and suicidal ideations. The use of this antidepressant by pregnant women may also result in severe life-threatening congenital birth defects.
Remeron Side Effects
The following is a comprehensive list of severe Remeron side effects that have been associated with the popular antidepressant:
- Chest pains
- Liver problems
- Bouts of mania
- Rapid heart rate
- Severe blood and bone marrow complications
- Agranulocytosis (condition responsible for irreversibly damaging bone marrow and prohibiting the production of white blood cells)
Remeron & Suicide
Patients diagnosed with major depressive disorders, both adult and pediatric, may demonstrate a propensity for the further development of depression and the emergence of suicidal ideation while receiving antidepressant treatment. Due to the increased link between Remeron and suicide, the FDA has issued a Public Health Advisory to update patients and healthcare providers with the latest information on this subject. According to the advisory, several variations of scientific literature have suggested that there is the possibility of an increased risk for suicidal behavior in adults who are being treated with antidepressant medications.
As of 2007, the FDA requested that the makers of antidepressant medications update their existing black box warnings to include the increased risk of suicidal thinking and behavior, known as suicidality, in young adults ages 18 to 24 during initial treatment. Due to the increased development of suicidal ideation, patients may contact a Remeron lawyer at The Senators (Ret.) Firm, LLP for a free case evaluation.
Remeron Birth Defects
The pharmacodynamics of mirtazapine may be responsible for a variety of associated Remeron birth defects with varying degrees of severity. Subsequently, Pregnant women who receive Remeron treatment may significantly increase their risk of giving birth to a child with one or more of the following congenital abnormalities:
- Atrial Septal Defects
- Ventricular Septal Defects
- Ebstein’s Anomaly
- Mitral Valve Defects
- Transposition of the Great Arteries
- Tetralogy of Fallot
- Hypoplastic Left Heart Syndrome (HLHS)
- Hypoplastic Right Heart Syndrome (HRHS)
- Tricuspid Valve Stenosis
- Tricuspid Atresia
- Aortic Stenosis
- Patent Ductus Arteriosus (PDA)
- Coarctation of the Aorta
- Truncus Arteriosus
- Heart Murmur
- Pulmonary Stenosis
- Pulmonary Atresia
- Gastroschisis – abdominal wall defect
- Esophageal Stenosis
- Esophageal Atresia
- Anal Atresia
- Spina Bifida
- Heart Malformations
- Neural Tube Defects
- Hand Deformations
- Cleft Lip
- Cleft Palate
- Fetal Death
- Growth Restriction
- Persistent Pulmonary Hypertension of the Newborn (PPHN)
- Mental Retardation
- Down’s Syndrome
- Dandy Walker Syndrome
- Undescended Testicles
- Cloacal Exstrophy
Due to the severity of these birth defects, patients may contact a lawyer at The Senators (Ret.) Firm, LLP for a free case evaluation of their potential Remeron lawsuit.
Remeron Bone Marrow Injury
Recent evidence suggests that extensive Remeron treatment may result in the suppression of bone marrow. Usually presented in the form of neutropenia or agranulocytosis, the suppression of bone marrow may result in severe, life-threatening circumstances. During the premarketing clinical trials, 2 out of 2,796 patients being treated with mirtazapine developed agranulocytosis. Subsequently, data revealed a third patient who developed severe neutropenia after taking mirtazapine-containing medications. For these three patients, onset of severe neutropenia was detected frequently throughout all phases of treatment.
Neutropenia is characterized by an abnormally low amount of white blood cells. More specifically, the significantly decreased ratio of neutrophils inhibits the body’s ability to fight infections and bacteria that enter the blood stream. Patients with neutropenia are more susceptible to bacterial infections and, without prompt medical attention, the condition may become life-threatening.
Similar to that of neutropenia, agranulocytosis is characterized by a distinct lack of white blood cells. It represents a severe lack of one major class of infection-fighting white blood cells. Therefore, those diagnosed with agranulocytosis are also at significant risk of developing serious infections due to their suppressed immune system.
Patients who develop a Remeron bone marrow injury, after taking the antidepressant, may contact a lawyer at The Senators (Ret.) Firm, LLP for a free case evaluation of their potential Remeron lawsuit.
Remeron Blood Complications
Mirtazapine’s distinct mechanism of action may coincide with several Remeron blood complications. Subsequently, antidepressants, such as Remeron, may affect blood glucose concentrations because of their indirect effects on the endocrine system. According to a controlled study, nonfasting cholesterol increased 20% beyond the normal limit in 15% of the patients treated with mirtazapine. In the same studies, nonfasting triglycerides increased in 6% of mirtazapine-treated patients compared to the 3% of patients who received a placebo. Remeron blood complications such as these may result in severe, adverse health events.
Do I Have a Remeron Lawsuit?
The trial lawyers at The Senators (Ret.) Firm, LLP have decades of experience navigating through complex legislative and regulatory issues and litigating high stakes cases all over the nation. Our law firm focuses on the representation of plaintiffs in Remeron lawsuits. We are currently accepting new cases in all 50 states.
Again, if you or a loved one has been injured by Remeron, you should contact our lawyers immediately by clicking the link below or calling toll free 1-800-773-0849. You may be entitled to compensation for your injuries and we can help.